Human Melanoma Inhibitory Activity Protein 3, MIA3 ELISA Kit

SKU: E5654Hu

Size:96 Tests-1 Kit

Background:Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum (PubMed: 27138255, PubMed: 21525241, PubMed: 25202031, PubMed: 27170179). Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum (PubMed: 27138255). Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity). Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites (PubMed: 21525241, PubMed: 25202031, PubMed: 27170179).

Research_area:Others

Applications:ELISA

Target_protein:MIA2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.149ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Melanoma Inhibitory Activity Protein 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96PC5

MASS(Da):159,836

GeneID:4253

Synonyms:CTAGE family member 5 ER export factor;Cutaneous T-cell lymphoma-associated antigen 5;Melanoma inhibitory activity protein 2;Meningioma-expressed antigen 6/11;MIA 2;MIA protein 2;MIA2

Gene names:MIA2

Standard solution:96ng/mL