Human Macrophage Inflammatory Protein-1Β, MIP-1B ELISA Kit

SKU: E0087Hu

Size:96 Tests-1 Kit

Background:Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

Research_area:Immunology

Applications:ELISA

Target_protein:CCL4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.22pg/ml

Detection range:0.5-150pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Macrophage Inflammatory Protein-1 beta

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P13236

MASS(Da):10,212

GeneID:3883726351

Synonyms:ACT-2;C-C motif chemokine 4;CCL 4;CCL4;G-26 T-lymphocyte-secreted protein;HC21;LAG-1;Lymphocyte activation gene 1 protein;Macrophage inflammatory protein 1-beta;MIP-1-beta;MIP-1-beta(1-69;MIP-1-beta(3-69;PAT 744;Protein H400;SIS-gamma;Small-inducible cytokine A4;T-cell activation protein 2

Gene names:CCL4

Standard solution:160pg/ml