Human LOXL2/Lysyl Oxidase Like 2 ELISA Kit PicoKine®

SKU: EK1391

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: LOXL2

Specificity: Natural and recombinant human LOXL2

Background: Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the LOXL2 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q26-Q774

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Reference:

Uniprot ID: Q9Y4K0

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4017

Protein Name: Lysyl oxidase homolog 2

Gene Full Name: lysyl oxidase like 2

Synonyms: lysyl oxidase like 2; LOR; LOR2; WS9-14; LOXL2