Human LOX-1/OLR1 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

SKU: EZ0824

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: OLR1

Specificity: Natural and recombinant human LOX-1/OLR1

Background: LOX-1 (lectin-type oxidized LDL receptor 1) also known as OLR1, is a protein that in humans is encoded by the OLR1 gene. LOX-1 is a receptor protein which belongs to the C-type lectin superfamily. The LOX1 gene is mapped to 12p13-p12 by fluorescence in situ hybridization. LOX1 is expressed on the plasma membrane of differentiated macrophages, but not on monocytes. The LOX1 protein acts as a macrophage scavenger receptor. LOX1 expression was detected in all choroidal neovascular membranes, regardless of structure, whereas there was no evidence of LOX1 within the posterior segments of normal eyes. LOX1 plays an active role in the pathogenesis of choroidal neovascularization, especially in ARMD.

Immunogen: Expression system for standard: NS0; Immunogen sequence: S61-Q273

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Reference:

Uniprot ID: P78380

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4973

Protein Name: Oxidized low-density lipoprotein receptor 1

Gene Full Name: oxidized low density lipoprotein receptor 1

Synonyms: CLEC8A; hLOX 1; Lectin like oxLDL receptor 1; LOX 1; LOX1; OLR1; Ox LDL receptor 1; SCARE1