Human KLK5/Kallikrein-5 ELISA Kit PicoKine®

SKU: EK0817

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: KLK5

Specificity: Natural and recombinant human KLK5

Background: Kallikrein gene 5 (KLK5, also known as KLK-L2), located on chromosome 19q13.4, is one of the newly identified members of the kallikrein gene family, which is a subgroup of the serine protease enzyme family. In normal human tissues, KLK5 is highly expressed in skin, mammary gland and testis. KLK5 has been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. It is proposed that KLK5 regulates this process since it is able to self-activate in addition to activating KLK7 and KLK14.

Immunogen: Expression system for standard: NS0; Immunogen sequence: V23-S293

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Reference:

Uniprot ID: Q9Y337

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 25818

Protein Name: Kallikrein-5

Gene Full Name: kallikrein related peptidase 5

Synonyms: Kallikrein 5; Kallikrein like protein 2; kallikrein related peptidase 5; KLK L2; KLK5; KLKL2; SCTE; Stratum corneum tryptic enzyme