Human KIT / SCFR / CD117 / c Kit ELISA Kit PicoKine®

SKU: EK0835

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: KIT

Specificity: Natural and recombinant human KIT

Background: SCFR (Mast/stem cell growth factor receptor), also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117, is a protein that in humans is encoded by the KIT gene. KIT was first described as the cellular homolog of the feline sarcoma viral oncogene v-kit. The KIT gene is mapped on 4q12. Kit was expressed on the surface of germ cells up to the pachytene stage. Signaling from the KIT receptor tyrosine kinase is essential for primordial germ cell growth both in vivo and in vitro. Determination of the KIT effectors acting in primordial germ cells has been hampered by the lack of effective methods to manipulate easily gene expression in these cells.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q26-T520

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Reference:

Uniprot ID: P10721

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3815

Protein Name: Mast/stem cell growth factor receptor Kit

Gene Full Name: KIT proto-oncogene, receptor tyrosine kinase

Synonyms: C Kit; CD117; c-Kit; c-Kit/CD117; KIT; PBT; Proto oncogene c Kit; SCFR; Tyrosine protein kinase Kit