Human KIM1 / TIM-1 ELISA Kit PicoKine®

SKU: EK0883

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: HAVCR1

Specificity: Natural and recombinant human KIM1

Background: KIM1 (TIM-1), also known as Hepatitis A virus cellular receptor 1, is a protein that in Rats is encoded by the HAVCR1 gene. Infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV led to conclude that the protein is indeed a receptor for the virus. Immunofluorescence microscopy demonstrated internalization of HAV by dog cells expressing HAVCR1. Using a monoclonal antibody to Rat Tim1, Tim1 was expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. By homology of synteny with the Rat Tim1 gene and database analysis, the HAVCR1 gene was mapped to 5q33.2.

Immunogen: Expression system for standard: NS0; Immunogen sequence: S21-T288

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Reference:

Uniprot ID: Q96D42

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 26762

Protein Name: Hepatitis A virus cellular receptor 1

Gene Full Name: hepatitis A virus cellular receptor 1

Synonyms: hepatitis A virus cellular receptor 1; CD365; HAVCR; HAVCR-1; KIM-1; KIM1; TIM; TIM-1; TIM1; TIMD-1; TIMD1; HAVCR1