Human Kallikrein 6, KLK6 ELISA Kit

SKU: E0863Hu

Size:96 Tests-1 Kit

Background:Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

Research_area:Cancer

Applications:ELISA

Target_protein:KLK6

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.21ng/ml

Detection range:0.5-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Kallikrein 6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q92876

MASS(Da):26,856

GeneID:5653

Synonyms:Kallikrein-6;KLK 6;KLK6;Neurosin;Protease M;Serine protease 18;Serine protease 9;SP59;Zyme;

Gene names:KLK6

Standard solution:80ng/ml