Human Interferon Regulatory Factor 4, IRF4 ELISA Kit

SKU: E3334Hu

Size:96 Tests-1 Kit

Background:Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).

Research_area:Tags & Cell Markers; Epigenetics and Nuclear Signaling; Cancer

Applications:ELISA

Target_protein:IRF4

Reactivity:Human

Assay type:Sandwich

Sensitivity:2.58ng/L

Detection range:5-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:interferon regulatory factor 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q15306

MASS(Da):51,772

GeneID:3662

Synonyms:Interferon regulatory factor 4;IRF4;IRF-4;LSIRF;Lymphocyte-specific interferon regulatory factor;Multiple myeloma oncogene 1;MUM1;NF-EM5;SHEP8;

Gene names:IRF4

Standard solution:2400ng/L