Human Intercellular Adhesion Molecule 1, ICAM-1 ELISA Kit

SKU: E0212Hu

Size:96 Tests-1 Kit

Background:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.

Research_area:Immunology

Applications:ELISA

Target_protein:ICAM1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.56ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Intercellular Adhesion Molecule 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P05362

MASS(Da):57,825

GeneID:3383

Synonyms:CD antigen CD54;ICAM 1;ICAM1;ICAM-1;Intercellular adhesion molecule 1;Major group rhinovirus receptor

Gene names:ICAM1

Standard solution:6400ng/L