Human Integrin Β4, ITΒ4 ELISA Kit

SKU: E3031Hu

Size:96 Tests-1 Kit

Background:Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed: 20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed: 22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed: 28873464).

Research_area:Others

Applications:ELISA

Target_protein:ITGB4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.23ng/ml

Detection range:0.5-200ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Integrin beta4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P16144

MASS(Da):202,167

GeneID:3691

Synonyms:CD antigen CD104;GP150;Integrin beta-4;ITGB 4;ITGB4

Gene names:ITGB4

Standard solution:240ng/ml