Human Inositol 1,4, 5-Trisphosphate Receptor Type 1, ITPR1 ELISA Kit

SKU: E5467Hu

Size:96 Tests-1 Kit

Background:Intracellular Channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate (PubMed: 27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:ITPR1

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.46ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Inositol 1,4,5-Trisphosphate Receptor Type 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14643

MASS(Da):313,929

GeneID:3708

Synonyms:Inositol 1,4,5-trisphosphate receptor type 1;InsP3R1;IP3 receptor isoform 1;IP3R 1;ITPR 1;ITPR1;Type 1 inositol 1,4,5-trisphosphate receptor;Type 1 InsP3 receptor

Gene names:ITPR1

Standard solution:960ng/L