Human IL-12(p70) PicoKine® Quick ELISA Kit

SKU: FEK0421

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL12A

Specificity:

Background: Interleukin(IL)-12 is a 70-KDa cytokine comprised of two disulfide-linked proteins(p35 and p40) and is essential for the initiation of effective immune response.[i] And the IL-12p70 is a heterodimer of p35 and p40 subunits; it is an important cytokine secreted by antigen-presenting cells in response to antigenic stimulation.[ii] Gene expression analysis of the IL-12 cytokine family subunits revealed that both strains induced high levels of p40(protein chain communal to IL-12 p70 and IL-23) as well as p19, a subunit of IL-23. Conversely only ACT- 18HS19 infection induced consistent transcription of IL-12 p35, a subunit of IL-12 p70.[iii] The standard product used in this kit is recombinant human IL-12 p70 with the molecular mass of 75 KDa.

Immunogen: Expression system for standard: NS0; Immunogen sequence: (I23-S328) + (R23-S219)

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: P29459

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 3592

Protein Name: Interleukin-12 subunit alpha

Gene Full Name: interleukin 12A

Synonyms: CLMF; CLMF p35; IL 12 subunit p35; IL 12A; IL12; IL-12; IL12A; IL-12A; Interleukin 12 subunit alpha; NFSK; NKSF1; P35