Human Growth Differentiation Factor 11, GDF11 ELISA Kit

SKU: E2267Hu

Size:96 Tests-1 Kit

Background:Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed: 28257634).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:GDF11

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.76ng/L

Detection range:10-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Growth Differentiation Factor 11

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O95390

MASS(Da):45,091

GeneID:10220

Synonyms:BMP-11;Bone morphogenetic protein 11;GDF 11;GDF11;GDF-11;Growth/differentiation factor 11

Gene names:GDF11

Standard solution:3200ng/L