Human GPVI ELISA Kit PicoKine®

SKU: EK2212

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: GP6

Specificity: Natural and recombinant human GP6

Background: Glycoprotein VI (platelet), also known as GPVI, is a glycoprotein receptor for collagen which is expressed in platelets. In humans, glycoprotein VI is encoded by the GPVI gene. This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q21-K267

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Reconstitution:

Reference:

Uniprot ID: Q9HCN6

Host:

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 51206

Protein Name: Platelet glycoprotein VI

Gene Full Name: glycoprotein VI platelet

Synonyms: GPIV; GPVI; BDPLT11; Platelet glycoprotein VI; Glycoprotein 6