Human Gp130/IL6ST ELISA Kit PicoKine®

SKU: EK0367

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL6ST

Specificity: Natural and recombinant human Sgp130

Background: GP130 (Glycoprotein 130) also known as IL6ST or CD130, is a transmembrane protein?which is the founding member of the class of all?cytokine receptors. The GP130 gene is mapped on 5q11.2. Gp130 showed an apparent molecular mass of 130 kD by SDS-PAGE. Gp130?is involved in the formation of high-affinity IL6-binding sites and in IL6 signal transduction. Sgp130 has a role in modulating signals transduced by membrane-bound?gp130. Gp130 is an important part of many different types of signaling complexes. Gp130 molecules with mutations in either of these segments could not transduce a growth signal.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L24-E619

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Reconstitution:

Reference:

Uniprot ID: P40189

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 3572

Protein Name: Interleukin-6 receptor subunit beta

Gene Full Name: interleukin 6 cytokine family signal transducer

Synonyms: CD130; CDw130; Glycoprotein 130; GP130; GP130 RAPS; IL 6 receptor subunit beta; IL 6R beta; IL 6R subunit beta; IL 6RB; IL6R beta; IL-6RB; IL6ST; IL-6ST; IL 6ST; Membrane glycoprotein 130