Human Glypican-1,GPC1 ELISA KIT

SKU: E2111Hu

Size:96 Tests-1 Kit

Background:Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. {ECO:0000250, ECO:0000269|PubMed:19936054, ECO:0000269|PubMed:21642435}.

Research_area:

Applications:ELISA

Target_protein:GPC1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.61ng/ml

Detection range:1.25-80ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Glypican 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P35052

MASS(Da):61680

GeneID:2817

Synonyms:GPC1

Gene names:GPC1

Standard solution:160ng/ml