Human Glutamate [NMDA] receptor subunit zeta-1,GRIN1 ELISA KIT

SKU: E1078Hu

Size:96 Tests-1 Kit

Background:Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761). {ECO:0000269|PubMed:26875626, ECO:0000269|PubMed:26919761, ECO:0000269|PubMed:28105280, ECO:0000269|PubMed:28126851, ECO:0000269|PubMed:7685113}.

Research_area:

Applications:ELISA

Target_protein:GRIN1

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.01ng/mL

Detection range:1.88-120ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Glutamate [NMDA] receptor subunit zeta-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q05586

MASS(Da):105373

GeneID:2902

Synonyms:GRIN1 NMDAR1

Gene names:GRIN1

Standard solution:240ng/mL