Human Formin-binding Protein 1, FNBP1 ELISA Kit

SKU: E3188Hu

Size:96 Tests-1 Kit

Background:May act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL.

Research_area:Others

Applications:ELISA

Target_protein:FNBP1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.55ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Formin-Binding Protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96RU3

MASS(Da):71,307

GeneID:23048

Synonyms:FNBP 1;FNBP1;Formin-binding protein 1;Formin-binding protein 17;hFBP17

Gene names:FNBP1

Standard solution:4800ng/L