Human FOLR2/Beta Fr ELISA Kit PicoKine®

SKU: EK1539

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: FOLR2

Specificity: Natural and recombinant human FOLR2

Background: Folate receptor beta is a protein that in humans is encoded by the FOLR2 gene. The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

Immunogen: Expression system for standard: NS0; Immunogen sequence: T17-N230

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: P14207

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 2350

Protein Name: Folate receptor beta

Gene Full Name: folate receptor beta

Synonyms: Folate receptor beta; FBP; FR-P3; FR-BETA; BETA-HFR; FBP/PL-1