Human Folate Receptor Alpha, FOLR1 ELISA Kit

SKU: E5300Hu

Size:96 Tests-1 Kit

Background:Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:FOLR1

Reactivity:Human

Assay type:Sandwich

Sensitivity:32.19ng/L

Detection range:70-15000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Folate Receptor Alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P15328

MASS(Da):29,819

GeneID:2348

Synonyms:Adult folate-binding protein;FBP;Folate receptor 1;Folate receptor alpha;Folate receptor, adult;FOLR 1;FOLR1;FR-alpha;KB cells FBP;Ovarian tumor-associated antigen MOv18

Gene names:FOLR1

Standard solution:16000ng/L