Human Flt3 Ligand ELISA Kit PicoKine®

SKU: EK0354

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: FLT3LG

Specificity: Natural and recombinant human Flt-3ligand

Background: Fms-related tyrosine kinase 3 ligand (FLT3LG), also known as Flt-3ligand or FL, is a protein which in humans is encoded by the FLT3LG gene. It is mapped to 19q13.3. Flt-3ligand is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating factor 1 (CSF-1). In synergy with other growth factors, Flt-3ligand stimulates the proliferation and differentiation of various blood cell progenitors. Besides that, Flt-3ligand can control the development of Dendritic cells (DCs) and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts. Flt-3ligand also can enhance the response of stem and primitive progenitor cells to other growth factors to generate all myeloid lineages except erythroid cells.

Immunogen: Expression system for standard: NS0; Immunogen sequence: T27-P185

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Uniprot ID: P49771

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 2323

Protein Name: Fms-related tyrosine kinase 3 ligand

Gene Full Name: fms related receptor tyrosine kinase 3 ligand

Synonyms: Fms related receptor tyrosine kinase 3 ligand; FL; FLG3L; FLT3L; FLT3LG