Human Ectonucleotide Pyrophosphatase , ENPP3 ELISA Kit

SKU: E5224Hu

Size:96 Tests-1 Kit

Background:Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (PubMed:29717535). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic cells (By similarity). Has also alkaline phosphodiesterase activity (PubMed:11342463).

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:ENPP3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.032ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Ectonucleotide pyrophosphatase/phosphodiesterase family member 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O14638

MASS(Da):100,124

GeneID:5169

Synonyms:B10;CD antigen CD203c [Includes: Alkaline phosphodiesterase I;CD203c;Ectonucleotide pyrophosphatase/phosphodiesterase family member 3;E-NPP 3;ENPP3;NPP3;NPPase;Nucleotide diphosphatase];Nucleotide pyrophosphatase;PD-IBETA;PDNP3;Phosphodiesterase I beta;Phosphodiesterase I/nucleotide pyrophosphatase 3

Gene names:ENPP3

Standard solution:24ng/ml