Human DSC2 ELISA Kit PicoKine®

SKU: EK2187

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: DSC2

Specificity: Natural and recombinant Human DSC2

Background: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.

Immunogen: Expression system for standard: NS0; Immunogen sequence: R136-R684

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Reference:

Uniprot ID: Q02487

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 1824

Protein Name: Desmocollin-2

Gene Full Name: desmocollin 2

Synonyms: ARVD11; Cadherin family member 2; CDHF2; desmocollin 2; Desmocollin 3; Desmosomal glycoprotein II; Desmosomal glycoprotein III; DG2; DGII/III; DSC2; DSC3