Human Dimethylaniline Monooxygenase [N-Oxide-Forming] 3, FMO3 ELISA Kit

SKU: E5185Hu

Size:96 Tests-1 Kit

Background:Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds (PubMed: 10759686, PubMed: 30381441). Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite (PubMed: 9776311). TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation (PubMed: 29981269).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:FMO3

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.36ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Dimethylaniline Monooxygenase [N-Oxide-Forming] 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P31513

MASS(Da):60,033

GeneID:2328

Synonyms:Dimethylaniline monooxygenase [N-oxide-forming] 3;Dimethylaniline oxidase 3;FMO 3;FMO form 2;FMO II;FMO3;Hepatic flavin-containing monooxygenase 3;Trimethylamine monooxygenase

Gene names:FMO3

Standard solution:2400ng/L