Human Cytochrome c-1,CYC1 ELISA KIT

SKU: E5156Hu

Size:96 Tests-1 Kit

Background:Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. Cytochrome c1 is a catalytic core subunit containing a c-type heme. It transfers electrons from the [2Fe-2S] iron-sulfur cluster of the Rieske protein to cytochrome c. {ECO:0000250|UniProtKB:P07143}.

Research_area:

Applications:ELISA

Target_protein:CYC1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.98ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cytochrome c-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P08574

MASS(Da):35422

GeneID:1537

Synonyms:CYC1

Gene names:CYC1

Standard solution:4800ng/L