Human Corticosteroid 11 Beta Dehydrogenase Isozyme 1, HSD11B1 ELISA Kit

SKU: E5120Hu

Size:96 Tests-1 Kit

Background:11β-Hydroxysteroid dehydrogenase type 1, also known as cortisone reductase, is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system. In these tissues, HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors. It belongs to the family of short-chain dehydrogenases.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:HSD11B1

Reactivity:Human

Assay type:Sandwich

Sensitivity:14.25ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Corticosteroid 11-beta-dehydrogenase isozyme 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P28845

MASS(Da):32,401

GeneID:3290

Synonyms:11-beta-HSD1;11-beta-hydroxysteroid dehydrogenase 1;11-DH;Corticosteroid 11-beta-dehydrogenase isozyme 1;CORTRD2;HDL;HSD11;HSD11B;HSD11B1;HSD11L;Short chain dehydrogenase/reductase family 26C member 1

Gene names:HSD11B1

Standard solution:9600ng/L