Human Complement Factor H/CFH ELISA Kit PicoKine®

SKU: EK1399

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CFH

Specificity: Natural and recombinant human CFH

Background: Complement factor H (CFH), originally known as beta-1H globulin, is a serum glycoprotein that regulates the function of the alternativecomplement pathway in fluid phase and on cellular surfaces. It binds to C3b, accelerates the decay of the alternative pathway convertase C3bBb, and also acts as a cofactor for complement factor I, another C3b inhibitor. The CFH gene is located on chromosome 1q32-q32.1 within a cluster of genes encoding the regulatory complement components of the activation of C3 (RCA for 'regulators of complement activation'). This gene cluster includes decay-accelerating factor (DAF), C4-binding protein (C4BPA and C4BPB), and the factor H-related genes CFHR1, CFHR2, CFHR3, CFHR4, and CFHR5, among others. The gene family has arisen by multiple duplication events.

Immunogen: Target protein isolated from human plasma

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Uniprot ID: P08603

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3075

Protein Name: Complement factor H

Gene Full Name: complement factor H

Synonyms: ARMD4; ARMS1; CFH; CFHL3; Complement factor H; Factor H; FH; FHL1; H factor 1; HF; HF1; HF2; HUS