Human Complement Factor B, CFB ELISA Kit

SKU: E0379Hu

Size:96 Tests-1 Kit

Background:Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Research_area:Immunology

Applications:ELISA

Target_protein:CFB

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.19μg/ml

Detection range:8-2000ug/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Complement Factor B

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P00751

MASS(Da):85,533

GeneID:629

Synonyms:C3/C5 convertase;CFB;Complement factor B;Complement factor B Ba fragment;Complement factor B Bb fragment;GBG;Glycine-rich beta glycoprotein;PBF2;Properdin factor B;

Gene names:CFB

Standard solution:2400μg/ml