Human Complement decay-accelerating factor,DAF ELISA KIT

SKU: E0267Hu

Size:96 Tests-1 Kit

Background:This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829). {ECO:0000269|PubMed:7525274, ECO:0000305|PubMed:28657829}.; (Microbial infection) Acts as a receptor for Coxsackievirus A21, coxsackieviruses B1, B3 and B5. {ECO:0000269|PubMed:9151867}.; (Microbial infection) Acts as a receptor for Human enterovirus 70 and D68 (Probable). {ECO:0000269|PubMed:8764022}.; (Microbial infection) Acts as a receptor for Human echoviruses 6, 7, 11, 12, 20 and 21. {ECO:0000269|PubMed:7525274, ECO:0000305|PubMed:12409401}.

Research_area:

Applications:ELISA

Target_protein:CD55

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.16ng/L

Detection range:5-1800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:decay-accelerating factor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P08174

MASS(Da):41400

GeneID:1604

Synonyms:CD55 CR DAF

Gene names:CD55

Standard solution:1920ng/L