Human Chemokine (C-C motif) ligand 4,CCL4 ELISA KIT

SKU: E4262hu

Size:96 Tests-1 Kit

Background:Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. {ECO:0000269|PubMed:10540332, ECO:0000269|PubMed:12070155, ECO:0000269|PubMed:8525373}.

Research_area:

Applications:ELISA

Target_protein:CCL4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.01ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Chemokine (C-C motif) ligand 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P13236

MASS(Da):10212

GeneID:388372

Synonyms:CCL4 LAG1 MIP1B SCYA4

Gene names:CCL4

Standard solution:16ng/ml