Human CES1 PicoKine® Quick ELISA Kit

SKU: FEK1813

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CES1

Specificity: Natural and recombinant Human CES1

Background: Liver carboxylesterase 1 also known as carboxylesterase 1 (CES1, hCE-1 or CES1A1) is an enzyme that in humans is encoded by the CES1 gene. This gene is mapped to 16q12.2. It encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Immunogen: Expression system for standard: NS0; Immunogen sequence: G18-L567

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Reference:

Uniprot ID: P23141

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 1066

Protein Name: Liver carboxylesterase 1

Gene Full Name: carboxylesterase 1

Synonyms: ACAT; Brain carboxylesterase hBr1; CE1; CEH; CES1; Cocaine carboxylesterase; Egasyn; HMSE; HMSE1; Liver carboxylesterase 1; PCE 1; REH; Retinyl ester hydrolase; Serine esterase 1; SES1; TGH; Triacylglycerol hydrolase