Human Cd9 Antigen, CD9 ELISA Kit

SKU: E5022Hu

Size:96 Tests-1 Kit

Background:Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PubMed: 8478605, PubMed: 14575715, PubMed: 18541721). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (PubMed: 12796480). Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity). Acts as a receptor for PSG17 (By similarity). Involved in platelet activation and aggregation (PubMed: 18541721). Regulates paranodal junction formation (By similarity). Involved in cell adhesion, cell motility and tumor metastasis (PubMed: 8478605, PubMed: 7511626).

Research_area:Immunology

Applications:ELISA

Target_protein:CD9

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.025ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Cd9 Antigen

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P21926

MASS(Da):25,416

GeneID:928

Synonyms:5H9 antigen;CD 9;CD antigen CD9;CD9;CD9 antigen;Cell growth-inhibiting gene 2 protein;Leukocyte antigen MIC3;Motility-related protein;MRP-1;p24;Tetraspanin-29;Tspan-29

Gene names:CD9

Standard solution:24ng/ml