Human CD74 ELISA Kit PicoKine®

SKU: EK2152

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CD74

Specificity: Natural and recombinant human CD74

Background: HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster of Differentiation 74), is a protein that in humans is encoded by the CD74 gene. The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen: Expression system for standard: CHO; Immunogen sequence: Q73-M232

Clonality:

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Reconstitution:

Reference:

Uniprot ID: P04233

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 972

Protein Name: HLA class II histocompatibility antigen gamma chain

Gene Full Name: CD74 molecule

Synonyms: CD74; DHLAG; HLADG; Ia GAMMA; Ii; p33