Human CD25/IL-2sR Alpha ELISA Kit PicoKine®

SKU: EK0400

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL2RA

Specificity: Natural and recombinant human CD25

Background: CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. The IL2R gene was mapped to 10p15-p14. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.

Immunogen: Expression system for standard: NS0; Immunogen sequence: E22-C213

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Reference:

Uniprot ID: P01589

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3559

Protein Name: Interleukin-2 receptor subunit alpha

Gene Full Name: interleukin 2 receptor subunit alpha

Synonyms: CD25; IDDM10; IL 2 RA; IL 2 receptor subunit alpha; IL 2R subunit alpha; IL2 RA; IL2R; IL2RA; interleukin 2 receptor, alpha; p55; TAC antigen; TCGFR