Human Cd163 Antigen, CD163 ELISA Kit

SKU: E0246Hu

Size:96 Tests-1 Kit

Background:Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.

Research_area:Immunology

Applications:ELISA

Target_protein:CD63

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.052ng/ml

Detection range:0.1-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Cd163 Antigen

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P08962

MASS(Da):25,637

GeneID:967

Synonyms:CD 63;CD antigen CD63;CD63;CD63 antigen;Granulophysin;LAMP-3;Lysosomal-associated membrane protein 3;Melanoma-associated antigen ME491;Ocular melanoma-associated antigen;OMA81H;Tetraspanin-30;Tspan-30

Gene names:CD63

Standard solution:32ng/ml