Human CCL21/6Ckine/Exodus 2 PicoKine® Quick ELISA Kit

SKU: FEK0555

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CCL21

Specificity: Natural and recombinant Human CCL21

Background: Chemokine(C-C motif) ligand 21(CCL21) is a small cytokine belonging to the CC chemokine family. This chemokine is also known as 6Ckine(because it has six conserved cysteine residues instead of the four cysteines typical to chemokines), exodus-2, and secondary lymphoid-tissue chemokine(SLC). By somatic cell hybrid and radiation hybrid analyses, mapped the SCYA21 gene to 9p13. Chemokines are a family of proteins that leukocyte migration and activation to inflammatory stimuli. CXC chemokine ligand 13(CXCL13), CC chemokine ligand 21(CCL21), and CCL19 are constitutively expressed in secondary lymphoid organs, where they control the placement of lymphocytes and dendritic cells. It was demonstrate that the local expression of homeostatic chemokines in nonlymphoid organs, such as the lung, plays an important role in protective immune responses.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: S24-P134

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Reference:

Uniprot ID: O00585

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 6366

Protein Name: C-C motif chemokine 21

Gene Full Name: C-C motif chemokine ligand 21

Synonyms: C-C motif chemokine ligand 21; 6Ckine; CKb9; ECL; SCYA21; SLC; TCA4; CCL21