Human Caspase 5,CASP5 ELISA KIT

SKU: E2255Hu

Size:96 Tests-1 Kit

Background:Thiol protease that acts as a mediator of programmed cell death (PubMed:29898893, PubMed:28314590). Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD): cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis (PubMed:29898893). During non-canonical inflammasome activation, cuts CGAS and may play a role in the regulation of antiviral innate immune activation (PubMed:28314590). {ECO:0000269|PubMed:28314590, ECO:0000269|PubMed:29898893}.

Research_area:

Applications:ELISA

Target_protein:CASP5

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.25ng/ml

Detection range:0.5-32ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Caspase 5

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P51878

MASS(Da):49736

GeneID:838

Synonyms:CASP5 ICH3

Gene names:CASP5

Standard solution:64ng/ml