Human Calsequestrin-1, CASQ1 ELISA Kit

SKU: E6588Hu

Size:96 Tests-1 Kit

Background:Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle (PubMed:28895244). Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca2+ ions (PubMed:28895244). Regulates the release of lumenal Ca2+ via the calcium release channel RYR1; this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca2+ entry (SOCE) activity (PubMed:27185316).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:CASQ1

Reactivity:Human

Assay type:Sandwich

Sensitivity:6.99ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Calsequestrin-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P31415

MASS(Da):45,160

GeneID:844

Synonyms:Calmitine;Calsequestrin, skeletal muscle isoform;Calsequestrin-1;CASQ;CASQ1;PDIB1;VMCQA

Gene names:CASQ1

Standard solution:3200ng/L