Human Cadherin-related Family Member 2, PCDH24 ELISA Kit

SKU: E6577Hu

Size:96 Tests-1 Kit

Background:Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation (PubMed:24725409). May also play a role in cell-cell adhesion and contact inhibition in epithelial cells (PubMed:12117771).

Research_area:Others

Applications:ELISA

Target_protein:PCDH24

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.18ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cadherin-related family member 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9BYE9

MASS(Da):141,543

GeneID:54825

Synonyms:Cadherin-related family member 2;PCDH24;PCLKC;PC-LKC;Protocadherin LKC;Protocadherin-24

Gene names:CDHR2

Standard solution:2400ng/L