Human CA12/Carbonic anhydrase 12 ELISA Kit PicoKine®

SKU: EK1942

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CA12

Specificity: Natural and recombinant human CA12

Background: Carbonic anhydrase 12 is an enzyme that in humans is encoded by the CA12 gene. It is mapped to 15q22.2. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene.

Immunogen: Expression system for standard: NS0; Immunogen sequence: A25-A354

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Reference:

Uniprot ID: O43570

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 771

Protein Name: Carbonic anhydrase 12

Gene Full Name: carbonic anhydrase 12

Synonyms: CA XII; CA12; Carbonate dehydratase XII; Carbonic anhydrase 12; carbonic anhydrase XII; CAXII; HsT18816; Tumor antigen HOM RCC 3.1.3