Human Bone Morphogenetic Protein Receptor 1A, BMPR-1A ELISA Kit

SKU: E1564Hu

Size:96 Tests-1 Kit

Background:On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:BMPR1A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.045ng/mL

Detection range:0.1-40ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Bone Morphogenetic Protein Receptor 1A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P36894

MASS(Da):60,198

GeneID:657

Synonyms:Activin receptor-like kinase 3;ALK-3;BMP type-1A receptor;BMPR 1A;BMPR1A;BMPR-1A;Bone morphogenetic protein receptor type-1A;CD antigen CD292;Serine/threonine-protein kinase receptor R5;SKR5

Gene names:BMPR1A

Standard solution:48ng/mL