Human Bone Morphogenetic Protein 2, BMP-2 ELISA Kit

SKU: E1989Hu

Size:96 Tests-1 Kit

Background:Induces cartilage and bone formation (PubMed: 3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed: 24362451).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:BMP2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.01ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Bone Morphogenetic Protein 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P12643

MASS(Da):44,702

GeneID:650

Synonyms:BMP 2;BMP2;BMP-2;BMP-2A;Bone morphogenetic protein 2;Bone morphogenetic protein 2A

Gene names:BMP2

Standard solution:16ng/ml