Human Beta-hexosaminidase A,HEXA ELISA KIT

SKU: E0859Hu

Size:96 Tests-1 Kit

Background:Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides (PubMed:11707436, PubMed:9694901, PubMed:8672428, PubMed:8123671). The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2 (PubMed:11707436). The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide (PubMed:11707436). Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A (PubMed:9694901, PubMed:8672428, PubMed:8123671). {ECO:0000269|PubMed:11707436, ECO:0000269|PubMed:8123671, ECO:0000269|PubMed:8672428, ECO:0000269|PubMed:9694901}.

Research_area:

Applications:ELISA

Target_protein:HEXA

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.016ng/ml

Detection range:0.03-9ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:β-hexosaminidase A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P06865

MASS(Da):60703

GeneID:3073

Synonyms:HEXA

Gene names:HEXA

Standard solution:9.6ng/ml