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GeneBio Systems

Human Autotaxin ELISA Kit PicoKine®

Human Autotaxin ELISA Kit PicoKine®

SKU:EK1655

Regular price £874.00 GBP
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Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ENPP2

Specificity: Natural and recombinant human total Autotaxin

Background: Autotaxin, also known as ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2), is an enzyme that in humans is encoded by the ENPP2 gene. The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen: Expression system for standard: NS0; Immunogen sequence: A36-I863

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Reference:

Uniprot ID: Q13822

Host:

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Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Observed Molecular Weight:

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Gene ID: 5168

Protein Name: Autotaxin

Gene Full Name: ectonucleotide pyrophosphatase/phosphodiesterase 2

Synonyms: ATX; ATX X; Autotaxin; E NPP 2; ENPP2; LysoPLD; PD IALPHA; PDNP2

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