Human Apoptosis regulator Bcl-2,Bcl2 ELISA KIT

SKU: E1832Hu

Size:96 Tests-1 Kit

Background:Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785). {ECO:0000269|PubMed:17418785, ECO:0000269|PubMed:18570871}.

Research_area:

Applications:ELISA

Target_protein:BCL2

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.61ng/L

Detection range:18.75-1200ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:B-cell leukemia;lymphoma 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P10415

MASS(Da):26266

GeneID:596

Synonyms:BCL2

Gene names:BCL2

Standard solution:2400ng/L