Human Ankyrin Repeat and Socs Box Protein 2, ASB2 ELISA Kit

SKU: E4952Hu

Size:96 Tests-1 Kit

Background:Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. [Isoform 1]: Enhances adhesion of hematopoietic cells to fibronectin through targeting of filamins FLNA and FLNB for proteasomal degradation, it is transiantly expressed during hematopoietic cell differentiation. [Isoform 2]: Involved in myogenic differentiation and targets filamin FLNB for proteasomal degradation but not filamin FLNA.

Research_area:Others

Applications:ELISA

Target_protein:ASB2

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.04ng/L

Detection range:5-1000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Ankyrin Repeat and Socs Box Protein 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96Q27

MASS(Da):65,084

GeneID:51676

Synonyms:Ankyrin repeat and SOCS box protein 2;ASB 2;ASB2;ASB-2

Gene names:ASB2

Standard solution:1280ng/L