Human ANGPTL3 ELISA Kit PicoKine®

SKU: EK1374

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ANGPTL3

Specificity: Natural and recombinant human ANGPTL3

Background: ANGPTL3, also known as Angiopoietin-like 3 or HYPLl, is a protein that in humans is encoded by the ANGPTL3 gene. It is mapped to 1p31.3. The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is expressed predominantly in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain, and the C-terminal fibrinogen (FBN)-like domain. ANGPTL3 also acts as dual inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL), and increases plasma triglyceride and HDL cholesterol in rodents. It can inhibit endothelial lipase to catalyze HDL-phospholipid and increase HDL-PL levels.

Immunogen: Expression system for standard: NS0; Immunogen sequence: S17-E460

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Reference:

Uniprot ID: Q9Y5C1

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 27329

Protein Name: Angiopoietin-related protein 3

Gene Full Name: angiopoietin like 3

Synonyms: ANG 5; Angiopoietin 5; angiopoietin like 3; Angiopoietin like protein 3; Angiopoietin related protein 3; ANGPT5; ANGPTL3