Human Angiopoietin-like protein 4,ANGPTL4 ELISA KIT

SKU: E3119Hu

Size:96 Tests-1 Kit

Background:Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism (PubMed:19270337, PubMed:21398697, PubMed:27929370, PubMed:29899144). May also play a role in regulating glucose homeostasis and insulin sensitivity (Probable). Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (PubMed:14583458, PubMed:17068295). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro) (PubMed:17068295). Depending on context, may modulate tumor-related angiogenesis (By similarity). {ECO:0000250|UniProtKB:Q9Z1P8, ECO:0000269|PubMed:14583458, ECO:0000269|PubMed:17068295, ECO:0000269|PubMed:19270337, ECO:0000269|PubMed:21398697, ECO:0000269|PubMed:27929370, ECO:0000269|PubMed:29899144, ECO:0000305|PubMed:29899519}.; [ANGPTL4 N-terminal chain]: Mediates inactivation of the lipoprotein lipase LPL, and thereby plays an important role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism (PubMed:19270337, PubMed:21398697, PubMed:27929370, PubMed:29899144). Has higher activity in LPL inactivation than the uncleaved protein (PubMed:19270337, PubMed:21398697). {ECO:0000269|PubMed:19270337, ECO:0000269|PubMed:21398697, ECO:0000269|PubMed:27929370, ECO:0000269|PubMed:29899144}.

Research_area:

Applications:ELISA

Target_protein:ANGPTL4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.04ng/ml

Detection range:0.1-6.4ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Angiopoietin-like protein 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9BY76

MASS(Da):45214

GeneID:51129

Synonyms:ANGPTL4 ARP4 HFARP PGAR PP1158 PSEC0166 UNQ171/PRO197

Gene names:ANGPTL4

Standard solution:12.8ng/ml