Human Angiopoietin 2, ANG-2 ELISA Kit

SKU: E1221Hu

Size:96 Tests-1 Kit

Background:Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:ANG-2

Reactivity:Human

Assay type:Sandwich

Sensitivity:2.49ng/L

Detection range:5-1000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Angiopoietin 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O15123

MASS(Da):56,919

GeneID:285

Synonyms:ANG 2;ANG-2;Angiopoietin-2

Gene names:ANG-2

Standard solution:1280ng/L